WELLscope

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Microwell Plate Scanner

The WELLscope is a microwell plate scanner that uses confocal laser excitation & fluorescence measurement technology to avoid reading errors typically encountered when imaging microwell plates. Unwanted signals are often caused by reflections from the surface meniscus of the liquid sample, from trapped air bubbles that may adhere to the sides and bottom of the microwells, and potentially from the microwell materials themselves. The WELLscope can greatly reduce these types of measurement errors and produce better images.

	Confocal design: greatly reduces background signal and improves the signal to noise ratio.
	Precision optics: patented optical design ensures accurate reading of every pixel.
	High sensitivity design with photomultiplier tube (PMT) detection.
	Wide choice of fluorophores excited via laser excitation (488nm, 532nm, 635nm option available).
	16 bit dynamic range and optimize the useful dynamic range with detector offset control and gain (sensitivity) control.
	16-bit TIFF image output.
	Data acquisition and image analysis software included.

Powerful Scanning Options to Deliver Better Results

	Pixel-by-pixel spectrum analysis.
	Simultaneous multiple fluorophore detection.

(please enquire for the prices of the above options)

Applications

	Detect minute quantities of fluorophores
	Assay research and development

Artifacts caused by the microwell-walls can be observed using confocal depth profiling.

Images of 4 microwells (within a 384-well plate) containing a fluorescent solution

Summary of WELLscope Advantages

Full Well

Partially Filled Well

Air bubbles trapped at bottom of well

Sides of well absorb fluorophore, or release contaminants into solution that may quench fluorophore

WELLscope